Guillain-Barre syndrome

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Definition
  1. Noun:
    • A neurological disorder: Guillain-Barré syndrome is an acute autoimmune disorder affecting the peripheral nervous system, characterized by rapid-onset muscle weakness, pain, and sometimes paralysis.
    • A specific medical condition: It is a form of polyneuritis (inflammation of multiple nerves) where the body's immune system mistakenly attacks part of its own peripheral nerves.
Usage Examples
  • Noun:
    • The patient was diagnosed with Guillain-Barré syndrome after experiencing sudden leg weakness.
    • Recovery from Guillain-Barré syndrome can be a long process, often requiring intensive therapy.
Advanced Usage
  • Medical Context: The term is used almost exclusively in medical, clinical, or patient-education contexts to describe this specific syndrome.
    • The neurologist explained that Guillain-Barré syndrome often follows a bacterial or viral infection.
Variants and Related Words
  • GBS: A common acronym for Guillain-Barré syndrome.
    • The doctor's notes indicated a history of GBS.
  • Acute inflammatory demyelinating polyneuropathy (AIDP): The most common form of Guillain-Barré syndrome.
  • Polyneuritis: A broader term for inflammation of several peripheral nerves.
Synonyms
  • Acute inflammatory polyradiculoneuropathy: A more technical synonym.
  • Landry's ascending paralysis: An older, historical term for a similar condition.
Notes on Meaning
  • This term refers specifically to a single, defined medical syndrome. It is a proper noun and is always capitalized.
  • The cause is idiopathic (unknown), but it is often preceded by an infection, which triggers an abnormal immune response.
Noun
  1. a form of peripheral polyneuritis characterized by pain and weakness and sometimes paralysis of the limbs; cause is unknown